Abz-Amyloid β/A4 Protein Precursor₇₇₀ (669-674)-EDDnp |
| Catalog No.GA20452 |
Intramolecularly quenched fluorescent substrate containing the ortho-aminobenzoyl (Abz) / N-(2,4-dinitrophenyl)ethylenediamine (EDDnp) groups as the donor / acceptor pair. It mimicks the wild-type (JMV2235) β-amyloid precursor protein (βAPP) sequence targeted by β-secretase BACE (β-site APP-cleaving activity). This FRET substrate is cleaved by BACE1, BACE2, and cathepsin D.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1802078-43-8
Sample solution is provided at 25 µL, 10mM.
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Intramolecularly quenched fluorescent substrate containing the ortho-aminobenzoyl (Abz) / N-(2,4-dinitrophenyl)ethylenediamine (EDDnp) groups as the donor / acceptor pair. It mimicks the wild-type (JMV2235) β-amyloid precursor protein (βAPP)
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
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