Glutaminyl Cyclase Inhibitor 3 |
| Catalog No.GC36156 |
Glutaminyl Cyclase Inhibitor 3 (compound 212 ), a designed anti-Alzheimer’s compound, is a potent human Glutaminyl Cyclase (GC) inhibitor, with an IC50 of 4.5 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2092921-50-9
Sample solution is provided at 25 µL, 10mM.
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Glutaminyl Cyclase Inhibitor 3 (compound 212 ), a designed anti-Alzheimer's compound, is a potent human Glutaminyl Cyclase (GC) inhibitor, with an IC50 of 4.5 nM. Glutaminyl Cyclase-IN-1 (compound 212) significantly reduced the brain concentrations of pyroform Aβ and total Aβ and restored cognitive functions[1]. IC50: 4.5 nM (hGC)[1].
[1]. Hoang VH, et al. Discovery of Potent Human Glutaminyl Cyclase Inhibitors as Anti-Alzheimer's Agents Based on Rational Design. J Med Chem. 2017 Mar 23;60(6):2573-2590.
Average Rating: 5 (Based on Reviews and 3 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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