HCH6-1 |
| Catalog No.GC36212 |
HCH6-1 is a potent and competitive dipeptide antagonist of Formyl peptide receptor 1 (FPR1).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1435265-06-7
Sample solution is provided at 25 µL, 10mM.
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HCH6-1 is a competitive antagonist of Formyl peptide receptor 1 (FPR1), an emerging therapeutic target for the discovery of drugs to treat neutrophilic inflammatory diseases. HCH6-1 is a selective FPR1 inhibitor and has protective effects against acute lung injury (ALI). HCH6-1 inhibits superoxide anion generation, elastase release, and chemotaxis in human neutrophils activated by fMLF (an FPR1 agonist).
[1]. Yang SC, et al. Dipeptide HCH6-1 inhibits neutrophil activation and protects against acute lung injury by blocking FPR1. Free Radic Biol Med. 2017 May;106:254-269
Average Rating: 5 (Based on Reviews and 38 reference(s) in Google Scholar.)
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