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LL-37, acetylated,amidated

Catalog No.GC36468 Copy One-Click Copy Product Info

LL-37, acetylated, amidated is a cathelicidin peptide LL-37 acetylated on the N-terminus and amidated on the C-terminus.

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LL-37, acetylated,amidated Chemical Structure

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5mg Please Inquire Please Inquire

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Sample solution is provided at 25 µL, 10mM.



Description of LL-37, acetylated,amidated

LL-37, acetylated, amidated is a cathelicidin peptide LL-37 acetylated on the N-terminus and amidated on the C-terminus. The single human cathelicidin peptide LL-37 has antimicrobial and anti-biofilm activity against multiple Gram-positive and Gram-negative human pathogens, and has wound-healing effects on the host[1].

[1]. Duplantier AJ, et al. The Human Cathelicidin Antimicrobial Peptide LL-37 as a Potential Treatment for PolymicrobialInfected Wounds. Front Immunol. 2013 Jul 3;4:143.

Chemical Properties of LL-37, acetylated,amidated

Cas No. SDF
Formula C207H343N61O53 M.Wt 4534.4
Solubility Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of LL-37, acetylated,amidated

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 220.5 μL 1.1027 mL 2.2054 mL
5 mM 44.1 μL 220.5 μL 441.1 μL
10 mM 22.1 μL 110.3 μL 220.5 μL
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In vivo Formulation Calculator (Clear solution) of LL-37, acetylated,amidated

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Review for LL-37, acetylated,amidated

Average Rating: 5 ★★★★★ (Based on Reviews and 13 reference(s) in Google Scholar.)

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