PF 05089771 |
| Catalog No.GC36877 |
PF 05089771 is a potent, orally active and selective arylsulfonamide Nav1.7 inhibitor, with IC50 values of 11 nM, 12 nM, 13 nM, 171 nM and 8 nM for hNav1.7, cynNav1.7, dogNav1.7,ratNav1.7, and musNav1.7, respectively.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1235403-62-9
Sample solution is provided at 25 µL, 10mM.
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PF 05089771 is a Nav1.7 channel blocker extracted from patent WO/2010/079443 A1, compound example 788, has an IC50 of 8.6 nM.
[1]. Norinder U, et al. QSAR investigation of NaV1.7 active compounds using the SVM/Signature approach and the Bioclipse Modeling platform. Bioorg Med Chem Lett. 2013 Jan 1;23(1):261-3. [2]. BEAUDOIN, et al. SULFONAMIDE DERIVATIVES. Patent WO/2010/079443 A1.
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