PRMT5-IN-1 |
| Catalog No.GC36969 |
PRMT5 IN-1, a hemiaminal, is a potent, selective protein arginine methyltransferase 5 (PRMT5) inhibitor with an IC50 of 11 nM for PRMT5/MEP50. PRMT5 IN-1 can be converted to aldehydes and react with C449 to form covalent adducts under physiological conditions.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2366149-83-7
Sample solution is provided at 25 µL, 10mM.
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PRMT5 IN-1, a hemiaminal, is a covalent protein arginine methyltransferase 5 (PRMT5) inhibitor with an IC50 of 11 nM for PRMT5/MEP50. PRMT5 IN-1 can be converted to aldehydes and react with C449 to form covalent adducts under physiological conditions[1]. IC50: 11 nM (PRMT5)[1]
[1]. https://www.ncbi.nlm.nih.gov/pubmed/31312404
Average Rating: 5 (Based on Reviews and 28 reference(s) in Google Scholar.)
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