iP300w |
Catalog No.GC50721 |
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
Potent p300/CBP inhibitor. Inhibits p300-mediated H3K9 acetylation (IC50 = 33 nM). Inhibits cytotoxicity of DUX4 and overexpression of DUX4 target genes in vitro. Also impairs DUX4-mediated transcription in an animal model of facioscapulohumeral muscular dystrophy (FSHD).
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Average Rating: 5
(Based on Reviews and 25 reference(s) in Google Scholar.)Review for iP300w
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