JMS 17-2 hydrochloride |
| Catalog No.GC50436 |
CX3CR1 antagonist
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2341841-07-2
Sample solution is provided at 25 µL, 10mM.
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Chemokine CX3CR1 (fractalkine receptor) antagonist. Inhibits fractalkine-induced ERK phosphorylation and decreases migration of breast cancer cells in vitro. Also inhibits circulating tumor cells from seeding into bone and reduces overall tumor burden in a breast cancer metastasis model.
Shen et al (2016) Novel small-molecule CX3CR1 antagonist impairs metastatic seeding and colonization of breast cancer cells. Mol. Cancer Res. 14 518 PMID:27001765
Average Rating: 5 (Based on Reviews and 8 reference(s) in Google Scholar.)
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