Leelamine (Synonyms: Dehydroabietylamine, NSC 2955) |
Catalog No.GC44048 |
Leelamine is a diterpene molecule whose name derives from the Sanskrit word leela which means "play".
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Cas No.: 1446-61-3
Sample solution is provided at 25 µL, 10mM.
Leelamine is a diterpene molecule whose name derives from the Sanskrit word leela which means "play". It has weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 µM. Leelamine inhibits pyruvate dehydrogenase kinase (PDK) with an IC50 value of 9.5 µM. Derivatives of leelamine exhibit anti-inflammatory activity and show moderate inhibition of phospholipase A2 activity from a variety of sources.
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