LY-3381916 (Synonyms: IDO1-IN-5) |
| Catalog No.GC33287 |
LY-3381916 is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2166616-75-5
Sample solution is provided at 25 µL, 10mM.
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LY-3381916 is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[1].
LY-3381916 (up to 100 µM) shows no obvious agonism of aryl hydrocarbon receptor (AHR)[1].
[1]. Frank C. Dorsey, et al. Abstract 5245: Identification and characterization of the IDO1 inhibitor LY3381916. Cancer Research. 2018, 78(13).
Average Rating: 5 (Based on Reviews and 35 reference(s) in Google Scholar.)
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