NNC45-0781 |
| Catalog No.GC31565 |
NNC45-0781 is a tissue-selective estrogen partial-agonist.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 207277-66-5
Sample solution is provided at 25 µL, 10mM.
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NNC45-0781 is a tissue-selective estrogen partial-agonist.
NNC45-0781 (NNC 45-0781) shows that it is a very promising tissue-selective estrogen agonist. Total serum cholesterol is significantly increased in the vehicle-treated group as compared to the sham animals. All of the animals receiving NNC45-0781 at doses of 10 nmol/g or higher, has significantly lower levels of total serum cholesterol as compared to the vehicle treated group[1].
[1]. Bury PS, et al. Synthesis and pharmacological evaluation of novel cis-3,4-diaryl-hydroxychromanes as high affinity partial agonists for the estrogen receptor. Bioorg Med Chem. 2002 Jan;10(1):125-45.
Average Rating: 5 (Based on Reviews and 9 reference(s) in Google Scholar.)
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