OMDM-1 (Synonyms: (S)Noleoyl Tyrosinol) |
| Catalog No.GC41362 |
Numerous analogs of arachidonoyl ethanolamide potentiate its biological activity.
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Cas No.: 616884-62-9
Sample solution is provided at 25 µL, 10mM.
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Numerous analogs of arachidonoyl ethanolamide potentiate its biological activity. This potentiation is ascribed either to inhibition of AEA reuptake into neurons or inhibition of fatty acid amide hydrolase (FAAH) within the neurons. OMDM-1 is an endocannabinoid analog specifically designed to be a potent and selective inhibitor of the cellular uptake of AEA. Structurally, OMDM-1 is the amide of (S)-tyrosinol with oleic acid . In RBL-2H3 cells, OMDM-1 inhibits the cellular uptake of tritiated AEA with an IC50 of 2.4 µM, with negligible effects on the CB1 receptor and VR1.
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