Orotidine 5′-monophosphate trisodium (Synonyms: Orotidine monophosphate trisodium; Orotidylic acid trisodium) |
| Catalog No.GC64296 |
Orotidine 5'-monophosphate trisodium is a pyrimidine nucleotide.
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Cas No.: 68244-58-6
Sample solution is provided at 25 µL, 10mM.
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Orotidine 5’-monophosphate trisodium is a pyrimidine nucleotide. Orotidine 5’-monophosphate trisodium is synthesized via the de novo synthesis pathway for DNA synthesis in a large number of microorganisms including M. tuberculosis, S. cerevisiae, S. typhimurium and P. falciparum to name a few. The synthesis of orotidine 5’-monophosphate trisodium uses phosphoribosyl pyrophosphate (PRPP) and orotic acid (OA) as the substrates catalyzed by orotate phosphoribosyltransferase (OPRT)[1].
[1]. Subrahmanyeswara Rao NN, et al. QM/MM reveals the sequence of substrate binding during OPRT action. Comput Biol Chem. 2018 Jun;74:31-38.
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