(+/-)-PPCC oxalate |
| Catalog No.GC50048 |
Selective sigma (σ) agonist (σ1> σ2)
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 932736-91-9
Sample solution is provided at 25 µL, 10mM.
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Selective sigma (σ) receptor ligand. Displays high affinity for σ1; also binds at σ2 sites (Ki = 1.5 nM and 50.8 nM respectively). Selective over a range of receptor types including dopaminergic and muscarinic receptors, DAT and SERT.
Prezzavento et al (2007) Novel sigma receptor ligands: synthesis and biological profile. J.Med.Chem. 50 951 PMID:17328523 |Prezzavento et al (2008) A new sigma ligand, (±)-PPCC, antagonizes kappa opioid receptor-mediated antinociceptive effect. Life Sci. 82 549 PMID:18261749 |Antonini et al (2009) Anti-amnesic properties of (±)-PPCC, a novel sigma receptor ligand, on cognitive dysfunction induced by selective cholinergic lesion in rats. J.Neurochem. 109 744 PMID:19245662
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
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