Prostaglandin B2-d4 (Synonyms: PGB2d4)

Name: Prostaglandin B2-d4
Brand: GlpBio
SKU: GC47984
Availability: InStock
Rating: 5 (14 reviews)

Catalog No.GC47984

An internal standard for the quantification of prostaglandin B₂

Products are for research use only. Not for human use. We do not sell to patients.

Prostaglandin B2-d4 Chemical Structure

Cas No.: 211105-23-6

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50 μg	$77.00	In stock
100 μg	$147.00	In stock
500 μg	$616.00	In stock
1 mg	$1,079.00	In stock

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Sample solution is provided at 25 µL, 10mM.

GlpBio Products Cited In Reputable Papers

Nature
610.7931 (2022): 366-372

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618, 1017–1023 (2023)

Cell
183.7 (2020): 1867-1883

Cell Research
31, 1291–1307 (2021)

Cell Research
33, 273–287 (2023)

Cell Research
33, 546–561 (2023)

Molecular Cancer
21.1 (2022): 1-17

Molecular Cancer
21.1 (2022): 1-18

Cancer Cell
39 (2021): 1-16

Cell Host Microbe
30.8 (2022): 1124-1138

Cell Host Microbe
31.5 (2023): 766-780

Cell Host Microbe
31.3 (2023): 418-43

Cell Metabolism
34.2 (2022): 240-255

Ann Rheum Dis
82(4): 533-545 (2023)

Cell Mol Immunol
20, 264–276 (2023)

Adv Funct Mater
33.35 (2023): 2214998

Description Chemical Properties Product Documents

Product Documents

Quality Control & SDS

View current batch:

Purity: >99.00%

Prostaglandin B₂ (PGB₂-d₄) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGB₂ by GC- or LC-mass spectrometry. PGB₂ is a non-enzymatic dehydration product resulting from the treatment of PGE₂ or PGA₂ with strong base. It has weak agonist activity on TP receptors and can increase pulmonary blood pressure in the rabbit at relatively high doses (5 mg/kg).¹

1.Liu, F., Orr, J.A., and Wu, J.Y.Prostaglandin B2-induced pulmonary hypertension is mediated by TXA2/PGH2 receptor stimulationJournal of the American Physiological Society1040L602-L607(1994)

Cas No.	211105-23-6	SDF
Synonyms	PGB2d4
Canonical SMILES	O=C1C(C/C=C\C([2H])([2H])C([2H])([2H])CC(O)=O)=C(/C=C/[C@@H](O)CCCCC)CC1
Formula	C20H26D4O4	M.Wt	338.5
Solubility	DMF: >75 mg/ml (from PGB2),DMSO: >50 mg/ml (from PGB2),Ethanol: >100 mg/ml (from PGB2),PBS pH 7.2: >2 mg/ml (from PGB2)	Storage	Store at -20°C
General tips	Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition	Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
		1 mg	5 mg	10 mg
	1 mM	2.9542 mL	14.771 mL	29.5421 mL
	5 mM	0.5908 mL	2.9542 mL	5.9084 mL
	10 mM	0.2954 mL	1.4771 mL	2.9542 mL

Molarity Calculator
Dilution Calculator

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal:μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 14 reference(s) in Google Scholar.)

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Prostaglandin B2-d4 (Synonyms: PGB2d4)

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