(R)-Omeprazole (sodium salt) (Synonyms: (R)-OMEP, (R)-OMP, (R)-OMZ) |
| Catalog No.GC41720 |
(R)-Omeprazole is the inactive isomer of omeprazole, a gastric proton-pump inhibitor.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 161796-77-6
Sample solution is provided at 25 µL, 10mM.
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(R)-Omeprazole is the inactive isomer of omeprazole , a gastric proton-pump inhibitor. A stereoselective hydroxylation of (R)-omeprazole is mediated primarily by cytochrome P450 (CYP) 2C19, whereas CYP3A4 favors sulfoxidation of the active (S)-enantiomer . (R)-Omeprazole has been shown to act as a reversible direct-acting and metabolism-dependent inhibitor of CYP2C19 in pooled human liver microsomes (IC50 = 8.1 µM).
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