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Home >> Signaling Pathways >> Immunology/Inflammation >> SIKs

SIKs

SIKs (salt-inducible kinases) are serine/threonine-protein kinase involved in various processes such as cell cycle regulation, gluconeogenesis and lipogenesis and tumor suppression etc.

Products for  SIKs

  1. Cat.No. Product Name Information
  2. GC33070 ARN-3236 An inhibitor of SIK2 ARN-3236 Chemical Structure
  3. GC11719 HG-9-91-01 HG-9-91-01 is a salt-inducible kinases (SIK) inhibitor, inhibited SIK1, SIK2, SIK3 with IC50 values of 0.92nM, 6.5nM and 19.4nM, respectively. HG-9-91-01 Chemical Structure
  4. GC62657 MRIA9 MRIA9 is an ATP-competitive, pan Salt-Inducible kinase (SIK) and PAK2/3 inhibitor, with IC50 values of 516 nM, 180 nM and 127 nM for SIK1, SIK2 and SIK3, respectively. MRIA9 Chemical Structure
  5. GC50108 MRT 67307 dihydrochloride Salt inducible kinase (SIK) inhibitor MRT 67307 dihydrochloride Chemical Structure
  6. GC39148 Pterosin B Pterosin B, a indanone found in bracken fern (Pteridium aquilinum), is an inhibitor of salt-inducible kinase 3 (Sik3) signaling. Pterosin B Chemical Structure
  7. GC62142 WH-4-025 WH-4-025 is a Salt-inducible kinase (SIK) inhibitor (WO2016023014 A2). WH-4-025 Chemical Structure
  8. GC31645 YKL-05-099 YKL-05-099 is a salt-inducible kinase (SIK) inhibitor. YKL-05-099 Chemical Structure
  9. GC37951 YKL-06-061 YKL-06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively. YKL-06-061 Chemical Structure
  10. GC39195 YKL-06-062 YKL-06-062 is a second-generation salt-inducible kinase (SIK) inhibitor with an IC50 of 2.12 nM/1.40 nM/2.86 nM, respectively. YKL-06-062 Chemical Structure

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