P-gp
P-gp (P-glycoprotein) is a ATP-binding cassette transproters which overepxressed in multidrug-resistance cancer cells. It functions in pumping drug out of cell and lower intracellular drug concentration.
Products for P-gp
- Cat.No. Product Name Information
- GC13375 Dofequidar fumarate MDR reversal agent
- GC10964 Estradiol 17-(β-D-Glucuronide) (sodium salt) Estradiol 17-(β-D-Glucuronide) sodium, a metabolite of estrogen, is well known to cause intrahepatic cholestasis in humans.
- GC17065 Estradiol 3-(β-D-Glucuronide) (sodium salt) substrate for multidrug resistance protein 2 (MRP2)
- GC25405 Evodine Evodine, a natural product extracted from Evodiae fructus (EF), is a biomarker for quality assessment of EF in the Chinese Pharmacopoeia. Evodine is a potent P-gp inhibitor.
- GC10391 Hypophyllanthin P-glycoprotein (P-gp) inhibitor
- GC16609 LY335979 (Zosuquidar 3HCL) Zosuquidar (LY335979) trihydrochloride is a P-glycoprotein (P-gp) inhibitor (Ki=59 nM). LY335979 (Zosuquidar 3HCL) shows anti-tumor activities, and can be used in acute myelogenous leukemia (AML) research.
- GC15795 Rhodamine 123 (chloride) Rhodamine 123 (chloride) (RH-123; R-22420) is a fluorescent dye (Λex=503 nm, Λem=527 nm).
- GC15570 Tariquidar A P-glycoprotein inhibitor
- GC10928 Tariquidar methanesulfonate, hydrate A P-glycoprotein inhibitor
- GC16672 Zosuquidar A modulator of P-gp