FLAP
FLAP (5-lipoxygenase activating protein) is an integral protein within the nuclear membrane and is necessary for the activation of 5-lipoxygenase and therefore for the production of leukotrienes.
Products for FLAP
- Cat.No. Product Name Information
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GC31839
AM 103
AM 103 is a potent and selective FLAP inhibitor, with an IC50 value of 4.2 nM.
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GC62422
Atuliflapon
AZD5718
Atuliflapon (AZD5718) is an orally active inhibitor of FLAP (5?Lipoxygenase activating protein), with an IC50 of 2 nM. -
GC12232
BAY-X 1005
BAY X 1005; DG-031
BAY-X 1005 (BAY X 1005; DG-031) is an orally active and selective 5-lipoxygenase activating protein (FLAP) inhibitor. -
GC69101
FEN1-IN-2
FEN1-IN-2 (compound 20) is an inhibitor of flap endonuclease 1 (FEN1), with IC50 values of 3 nM and 226 nM for FEN1 and XPG, respectively.
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GC73487
FEN1-IN-5
FEN1-IN-5 (compound 12A) is a potent inhibitor of Flap endonuclease-1 (FEN1, IC50=12 nM), involving in DNA repair.
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GC31689
Fiboflapon (GSK2190915)
AM803
Fiboflapon (GSK2190915) (GSK2190915; AM-803) is a potent and orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood. -
GC15506
GSK2190915 sodium salt
GSK2190915 sodium salt; AM-803 sodium
GSK2190915 sodium salt (GSK2190915; AM-803) is a potent and orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood. -
GC12277
MK 886
L-663,536
FLAP and PPARα inhibitor, inhibits leukotriene biosynthesis -
GC11457
MK-0591
L-686,708, Quiflapon
An inhibitor of FLAP -
GC37059
Quiflapon sodium
Quiflapon sodium (MK-591 sodium) is a selective and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor.