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Home >> Signaling Pathways >> Tyrosine Kinase >> PTKs/RTKs

PTKs/RTKs

Receptor tyrosine kinases transfer phosphate from ATP to protein. They play a vital role in various cellular processes including regulation of cell growth, proliferation, differentiation and metabolism etc.

Products for  PTKs/RTKs

  1. Cat.No. Product Name Information
  2. GC72974 Entrectinib-d8

    NMS-E628-d8; RXDX-101-d8

     Entrectinib-d8 (NMS-E628-d8; RXDX-101-d8) is a deuterated version of Entrectinib. Entrectinib-d8 Chemical Structure
  3. GC73980 GGTI-2417 GGTI-2417 is a potent and selective inhibitor of GGTase I. GGTI-2417 Chemical Structure
  4. GC13902 KRCA 0008 Ack1 and anaplastic lymphoma kinase (ALK) dual inhibitor KRCA 0008 Chemical Structure
  5. GC16798 LDN-211904 LDN-211904 (compound 32) is a potent and selective EphB3 inhibitor with an IC50 of 0.079 μM. LDN-211904 shows good metabolic stability in mouse liver microsomes. LDN-211904 with cetuximab could be effective in inhibiting STAT3-activated CSC stemness and cetuximab resistance in CRC. LDN-211904 Chemical Structure
  6. GC73482 PF-07284892

    ARRY-558

     PF-07284892 (ARRY-558) is a potent and orally active SHP2 inhibitor with an IC50 value of 21 nM. PF-07284892 Chemical Structure
  7. GC74371 Pinealon Pinealon is a 3-amino acid peptide and shows neuroprotective properties. Pinealon Chemical Structure
  8. GC73232 PRDX1-IN-1 PRDX1-IN-1 is a selective inhibtor of PRDX1 with an IC50 value of 0.164 μM. PRDX1-IN-1 Chemical Structure
  9. GC14733 SU14813

    SU-14813;SU 14813

     A dual VEGFR and PDGFR family kinase inhibitor SU14813 Chemical Structure
  10. GC72930 XMU-MP-2 XMU-MP-2 is a BRK inhibitor with significant inhibitory activity on BRK-positive cells. XMU-MP-2 Chemical Structure

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