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Inicio >> Signaling Pathways >> Neuroscience

Neuroscience

Neuroscience

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides).

Targets for  Neuroscience

Products for  Neuroscience

  1. Cat.No. Nombre del producto Información
  2. GC63267 α-​Chaconine La α-chaconina inhibe las expresiones de COX-2, IL-1β, IL-6 y TNF-α a nivel transcripcional. α-​Chaconine Chemical Structure
  3. GC49097 α-Conotoxin AuIB (trifluoroacetate salt) A conotoxin and an antagonist of α3β4 subunit-containing nAChRs α-Conotoxin AuIB (trifluoroacetate salt) Chemical Structure
  4. GC26093 α-Conotoxin GI α-Conotoxin GI, a 13-residue peptide originally isolated from the venom of the fish-hunting cone snail Conus geographus, acts as a competitive antagonist for the muscle-type nicotinic acetylcholine receptor (nAChR) with excellent selectivity for α/δ receptor subunit binding over α/γ. α-Conotoxin GI Chemical Structure
  5. GC49140 α-Conotoxin ImI (trifluoroacetate salt) A conotoxin and an antagonist of α7 nAChRs α-Conotoxin ImI (trifluoroacetate salt) Chemical Structure
  6. GC49838 α-Cortolone A metabolite of cortisol α-Cortolone Chemical Structure
  7. GC40262 α-Humulene α-El humuleno es un constituyente principal de Tanacetum vulgare L. α-Humulene Chemical Structure
  8. GC64563 α-Methylserotonin α-Methylserotonin Chemical Structure
  9. GC48292 α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) α-MSH (α-Melanocyte-Stimulating Hormone) TFA, un neuropéptido endÓgeno, es un agonista endÓgeno del receptor 4 de melanocortina (MC4R) con actividades antiinflamatorias y antipiréticas. α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) Chemical Structure
  10. GC41499 α-Phellandrene α-Phellandrene is a cyclic monoterpene that has been found in various plants, including Cannabis, and has diverse biological activities. α-Phellandrene Chemical Structure
  11. GC10873 α-Spinasterol α-La espinasterol, aislada de Spinacia oleracea, tiene actividad antibacteriana. α-Spinasterol Chemical Structure
  12. GC63615 α-Thujone α-La tujona es un monoterpeno aislado del aceite esencial de Thuja occidentalis con potentes actividades antitumorales. α-Thujone Chemical Structure
  13. GC70179 α7 Nicotinic receptor agonist-1

    α7 Agonista del receptor nicotínico-1 (Preparación 5) es un agonista del receptor nAChR α7. El Agonista del receptor nicotínico-1 α7 se puede utilizar en trastornos psiquiátricos (como la esquizofrenia, el trastorno bipolar o depresión maníaca y la ansiedad) y discapacidades intelectuales (como la enfermedad de Alzheimer, los déficits de aprendizaje, los déficits cognitivos, el trastorno por déficit de atención e hiperactividad, pérdida de memoria y demencia con cuerpos de Lewy) para investigación.

     α7 Nicotinic receptor agonist-1 Chemical Structure
  14. GC49467 β-Aescin A triterpenoid saponin with diverse biological activities β-Aescin Chemical Structure
  15. GC63273 β-Amyloid (1-14),mouse,rat β-Amyloid (1-14),mouse,rat Chemical Structure
  16. GC66089 β-Amyloid (1-40) (TFA) β-Amyloid (1-40) TFA es una proteÍna primaria en las placas que se encuentran en los cerebros de pacientes con la enfermedad de Alzheimer's. β-Amyloid (1-40) (TFA) Chemical Structure
  17. GC70182 β-Amyloid (1-40), FAM-labeled TFA

    β-Amiloide (1-40), TFA marcado con FAM, es un péptido de β-amiloide (1-40) marcado con fluorescencia FAM (Λex= 492 nm y Λem= 518 nm).

     β-Amyloid (1-40), FAM-labeled TFA Chemical Structure
  18. GC63274 β-Amyloid (1-42), (rat/mouse) (TFA) β-Amyloid (1-42), (rat/mouse) (TFA) Chemical Structure
  19. GC37984 β-Amyloid (1-42), rat β-amiloide (1-42), la rata es un péptido de 42 aa, muestra un efecto citotÓxico en cortes agudos del hipocampo y se utiliza en la investigaciÓn de la enfermedad de Alzheimer's. β-Amyloid (1-42), rat Chemical Structure
  20. GC66416 β-Amyloid (22-35) (TFA) β-Amyloid 22-35 (Amyloid β-Protein 22-35) TFA, el fragmento de residuos 22-35 de β-proteÍna amiloide, tiene un efecto citotÓxico en neuronas cultivadas del hipocampo de rata en medio sin suero. β-Amyloid 22-35 TFA forma agregados y fibrillas amiloides tÍpicas que se asemejan a las de la β-proteÍna amiloide en soluciÓn tampÓn neutra). β-Amyloid (22-35) (TFA) Chemical Structure
  21. GC66346 β-Amyloid (42-1), human TFA β-amiloide (42-1), TFA humano es la forma inactiva de amiloide β Péptido (1-42). β-Amyloid (42-1), TFA humano es un péptido de 42 aminoÁcidos que juega un papel clave en la patogénesis de la enfermedad de Alzheimer. β-Amyloid (42-1), human TFA Chemical Structure
  22. GC37986 β-Amyloid 1-17 β-Amyloid 1-17 es un péptido de β-amiloide, estabiliza las fibras y juega un papel en la formación de fibras Aβ. β-Amyloid 1-17 Chemical Structure
  23. GC37987 β-Amyloid 1-20 β-Amyloid 1-20 consta de los aminoácidos 1 a 20 de la proteína beta amiloide. β-Amyloid 1-20 Chemical Structure
  24. GC37993 β-Amyloid 1-9 β-Amyloid 1-9, un fragmento N-terminal de beta amiloide, consta de los residuos de aminoácidos 1 a 9. β-Amyloid 1-9 Chemical Structure
  25. GC37985 β-Amyloid 11-22 β-Amyloid 11-22 es un fragmento peptídico de β-amiloide. β-Amyloid 11-22 Chemical Structure
  26. GC37988 β-Amyloid 12-20 β-Amyloid 12-20 es un fragmento peptídico de β-amiloide. β-Amyloid 12-20 Chemical Structure
  27. GC37991 β-Amyloid 15-21 β-Amyloid 15-21 Chemical Structure
  28. GC37992 β-Amyloid 18-28 β-Amyloid 18-28 es un fragmento peptídico de β-amiloide. β-Amyloid 18-28 Chemical Structure
  29. GC37994 β-Amyloid 22-40 β-Amyloid 22-40 es un fragmento peptídico de β-amiloide. β-Amyloid 22-40 Chemical Structure
  30. GC37995 β-Amyloid 33-40 β-Amyloid 33-40 es un péptido que consiste en el aminoácido 33 a 40 de la proteína beta amiloide. β-Amyloid 33-40 Chemical Structure
  31. GC37996 β-Amyloid 35-42 β-Amyloid 35-42 es un péptido que consiste en el aminoácido 35 a 42 de la proteína beta amiloide. β-Amyloid 35-42 Chemical Structure
  32. GC37997 β-Amyloid 4-10 β-Amyloid 4-10 es un epítopo para el anticuerpo policlonal anti-Aβ(1-42), reduce la deposición de amiloide en un modelo de ratón transgénico con enfermedad de Alzheimer. β-Amyloid 4-10 Chemical Structure
  33. GC34944 β-CGRP, human TFA β-CGRP, human TFA Chemical Structure
  34. GC41623 β-Elemonic Acid β-El Ácido elemÓnico es un triterpeno aislado de Boswellia papyrifera. β-Elemonic Acid Chemical Structure
  35. GC45234 β-Endorphin (1-27) (human) (trifluoroacetate salt) β-Endorphin (1-27) is an endogenous peptide that binds to μ-, δ-, and κ-opioid receptors (Kis = 5.31, 6.17, and 39.82 nM, respectively, in COS-1 cells expressing rat receptors). β-Endorphin (1-27) (human) (trifluoroacetate salt) Chemical Structure
  36. GC45236 β-Endorphin (rat) β-Endorphin (β-EP) is an endogenous opioid neuropeptide with diverse biological activities. β-Endorphin (rat) Chemical Structure
  37. GC52494 β-Endorphin (rat) (trifluoroacetate salt) An opioid neuropeptide β-Endorphin (rat) (trifluoroacetate salt) Chemical Structure
  38. GC49769 β-Glucogallin A plant metabolite and an aldose reductase 2 inhibitor β-Glucogallin Chemical Structure
  39. GC40105 βARK1 Inhibitor βInhibidor de ARK1 (5-[2-(5-nitro-2-furil)vinil]-2-furoato de metilo) es un inhibidor de GRK2 (β-ARK1). βARK1 Inhibitor Chemical Structure
  40. GC38010 γ-Aminobutyric acid γ-Aminobutyric acid Chemical Structure
  41. GC64508 γ-Aminobutyric acid-d6

    El ácido γ-aminobutírico-d6 (ácido 4-aminobutírico-d6) es el ácido γ-aminobutírico etiquetado con deuterio.

     γ-Aminobutyric acid-d6 Chemical Structure
  42. GC49865 γ-D-Glutamylglycine (trifluoroacetate salt) An excitatory amino acid antagonist γ-D-Glutamylglycine (trifluoroacetate salt) Chemical Structure
  43. GC48313 γ-Lindane An insecticide and GABAA receptor antagonist γ-Lindane Chemical Structure
  44. GC10872 α-Conotoxin AuIB α-Conotoxin AuIB, a potent and selective α3β4 nicotinic acetylcholine receptor (nAChR) antagonist, blocks α3β4 nAChRs expressed in Xenopus oocytes with an IC50 of 0.75 μM. α-Conotoxin AuIB Chemical Structure
  45. GC13644 α-Conotoxin EI Selective antagonist of neuromuscular nicotinic receptors α1β1γδ α-Conotoxin EI Chemical Structure
  46. GC14353 α-Conotoxin ImI Nicotinic receptor antagonist α-Conotoxin ImI Chemical Structure
  47. GC14296 α-Conotoxin PIA α-Conotoxin PIA es un antagonista del receptor nicotÍnico de acetilcolina (nAChR) que se dirige a los subtipos de nAChR que contienen las subunidades α6 y α3. α-Conotoxin PIA Chemical Structure
  48. GC10368 α-Conotoxin PnIA α-Conotoxin PnIA, un antagonista potente y selectivo del α7 nAChR de mamÍferos, tiene potencial para la investigaciÓn de afecciones neurolÓgicas como el dolor neuropÁtico y la enfermedad de Alzheimer's. α-Conotoxin PnIA Chemical Structure
  49. GC11577 α-Methyl-5-hydroxytryptamine maleate 5-HT2B receptor agonist α-Methyl-5-hydroxytryptamine maleate Chemical Structure
  50. GC34242 β-Amyloid (1-42), rat TFA β-Amyloid (1-42), rat TFA Chemical Structure
  51. GC31146 β-Amyloid (10-35), amide β-amiloide (10-35), la amida se compone de 26 aa (10-35 residuos del péptido Aβ) y es el componente principal de las placas amiloides de la enfermedad de Alzheimer. β-Amyloid (10-35), amide Chemical Structure
  52. GC31129 β-Amyloid 1-16 (Amyloid β-Protein (1-16)) β-Amyloid 1-16 (Amyloid β-Protein (1-16)) es un fragmento de proteÍna β-Amyloid involucrado en la uniÓn de metales. β-Amyloid 1-16 (Amyloid β-Protein (1-16)) Chemical Structure
  53. GC31171 β-Amyloid 1-28 (Amyloid β-Protein (1-28)) β-Amyloid 1-28 (Amyloid β-Protein (1-28)) es un fragmento de proteÍna β-Amyloid involucrado en la uniÓn de metales. β-Amyloid 1-28 (Amyloid β-Protein (1-28)) Chemical Structure
  54. GC30325 β-Amyloid 22-35 (Amyloid β-Protein (22-35)) β-Amyloid 22-35 (Amyloid β-Protein 22-35), el fragmento de residuos 22-35 de β-proteÍna amiloide, tiene un efecto citotÓxico en neuronas cultivadas del hipocampo de rata en medio sin suero. β-Amyloid 22-35 (Amyloid β-Protein (22-35)) Chemical Structure
  55. GC31137 β-Amyloid 29-40 (Amyloid beta-protein(29-40)) β-amiloide 29-40 (proteÍna beta amiloide (29-40)) es un fragmento de amiloide-β péptido β-Amyloid 29-40 (Amyloid beta-protein(29-40)) Chemical Structure
  56. GC31179 β-Amyloid 31-35 β-Amyloid 31-35 es la secuencia más corta del péptido amiloide-β nativo que retiene la actividad neurotóxica. β-Amyloid 31-35 Chemical Structure
  57. GC11449 β-CCB

    benzodiazepine receptor ligand

     β-CCB Chemical Structure
  58. GC33595 β-CGRP, human (Human β-CGRP)

    β-CGRP humano (Human β-CGRP) es uno de los péptidos calcitonina, actúa a través del complejo receptor similar a la calcitonina (CRLR) y proteína moduladora de actividad del receptor (RAMP), con IC50s de 1 nM y 300 nM para CRLR/RAMP1 y CRLR/RAMP2 en células.

     β-CGRP, human (Human β-CGRP) Chemical Structure
  59. GC18033 γDGG γDGG es un bloqueador competitivo del receptor AMPA. γDGG Chemical Structure
  60. GC52013 (±)-10-hydroxy-12(Z)-Octadecenoic Acid An oxylipin and metabolite of linoleic acid (±)-10-hydroxy-12(Z)-Octadecenoic Acid Chemical Structure
  61. GC52421 (±)-10-hydroxy-12(Z)-Octadecenoic Acid-d5 An internal standard for the quantification of (±)-10-hydroxy-12(Z)-octadecenoic acid (±)-10-hydroxy-12(Z)-Octadecenoic Acid-d5 Chemical Structure
  62. GC41657 (±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (hydrobromide) (±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (6,7-ADTN) is a dopamine receptor agonist (EC50s = 3.5 and 0.65 μM in rat striatal and nucleus accumbens homogenates, respectively). (±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (hydrobromide) Chemical Structure
  63. GC41658 (±)-2-hydroxy Ibuprofen (±)-2-hidroxi ibuprofeno es un metabolito de ibuprofeno. (±)-2-hydroxy Ibuprofen Chemical Structure
  64. GC62726 (±)-Amiflamine (±)-amiflamina (FLA 336) es un potente inhibidor de la monoaminooxidasa-A (MAO-A) con un pIC50 de 5,57. (±)-Amiflamine Chemical Structure
  65. GC46272 (±)-Asenapine-13C-d3 (hydrochloride) An internal standard for the quantification of (±)-asenapine (±)-Asenapine-13C-d3 (hydrochloride) Chemical Structure
  66. GC46274 (±)-Baclofen-d4 (±)-Baclofen-d4 es el deuterio etiquetado como Baclofen. (±)-Baclofen-d4 Chemical Structure
  67. GC60394 (±)-Duloxetine hydrochloride El clorhidrato de (±)-duloxetina ((Rac)-duloxetina) es el racemato del clorhidrato de duloxetina. (±)-Duloxetine hydrochloride Chemical Structure
  68. GC14410 (±)-Epibatidine nicotinic agonist (±)-Epibatidine Chemical Structure
  69. GC46288 (±)-Epibatidine (hydrochloride) An agonist of α4β2 subunit-containing nAChRs (±)-Epibatidine (hydrochloride) Chemical Structure
  70. GC46290 (±)-Ibuprofen-d3 El ibuprofeno D3 es un ibuprofeno etiquetado con deuterio. (±)-Ibuprofen-d3 Chemical Structure
  71. GC49515 (±)-Ibuprofen-d3 (sodium salt) An internal standard for the quantification of (±)-ibuprofen (±)-Ibuprofen-d3 (sodium salt) Chemical Structure
  72. GC45278 (±)-Ketoprofen-d3   (±)-Ketoprofen-d3 Chemical Structure
  73. GC12699 (±)-LY 395756 ligand for mGlu2 and mGlu3 receptor (±)-LY 395756 Chemical Structure
  74. GC16735 (±)-McN 5652

    5-HT uptake inhibitor

     (±)-McN 5652 Chemical Structure
  75. GC49875 (±)-N-desmethyl Venlafaxine (hydrochloride) A minor active metabolite of venlafaxine (±)-N-desmethyl Venlafaxine (hydrochloride) Chemical Structure
  76. GC46305 (±)-Nicotine-d3 An internal standard for the quantification of (±)-nicotine (±)-Nicotine-d3 Chemical Structure
  77. GC14834 (±)-Nipecotic acid GABA uptake inhibitor (±)-Nipecotic acid Chemical Structure
  78. GC41676 (±)-Nornicotine (±)-Nornicotine is a metabolite of nicotine that acts as a neuronal nicotinic acetylcholine receptor (nAChR) agonist. (±)-Nornicotine Chemical Structure
  79. GC49482 (±)-Nornicotine-d4 An internal standard for the quantification of (±)-nornicotine (±)-Nornicotine-d4 Chemical Structure
  80. GC12394 (±)-trans-ACPD (±)-trans-ACPD, un agonista de los receptores metabotrópicos, produce movilización de calcio y una corriente interna en neuronas de Purkinje cerebelosas cultivadas. (±)-trans-ACPD Chemical Structure
  81. GC11128 (±)-Vesamicol hydrochloride (±)-clorhidrato de vesamicol ((±)-clorhidrato de AH5183) es un potente inhibidor del transporte vesicular de acetilcolina con una Ki de 2 nM. (±)-Vesamicol hydrochloride Chemical Structure
  82. GC41685 (±)-WIN 55,212 (mesylate) (±)-WIN 55,212-2 is a potent aminoalkylindole cannabinoid (CB) receptor agonist with a Ki value of 62.3 and 3.3 nM for human recombinant central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, respectively. (±)-WIN 55,212 (mesylate) Chemical Structure
  83. GC41213 (±)10-HDHA

    (±)10-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.

     (±)10-HDHA Chemical Structure
  84. GC41214 (±)11-HDHA (±)11-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. (±)11-HDHA Chemical Structure
  85. GC40467 (±)11-HETE (±)11-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. (±)11-HETE Chemical Structure
  86. GC40802 (±)12(13)-DiHOME

    (±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME, a cytochrome P450-derived epoxide of linoleic acid also known as isoleukotoxin.

     (±)12(13)-DiHOME Chemical Structure
  87. GC41191 (±)13(14)-EpDPA (±)13(14)-EpDPA (13,14-EpDPE) es el producto de la reacción de la epoxigenasa del citocromo P-450 con ácido docosahexaenoico (DHA). (±)13(14)-EpDPA Chemical Structure
  88. GC41192 (±)13-HDHA (±)13-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. (±)13-HDHA Chemical Structure
  89. GC41193 (±)14-HDHA (±)14-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. (±)14-HDHA Chemical Structure
  90. GC41194 (±)16(17)-EpDPA

    EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators.

     (±)16(17)-EpDPA Chemical Structure
  91. GC41196 (±)16-HDHA (±)16-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. (±)16-HDHA Chemical Structure
  92. GC41197 (±)17-HDHA (±)17-HDHA is an autoxidation product of docosahexaenoic acid in vitro. (±)17-HDHA Chemical Structure
  93. GC41199 (±)19(20)-EpDPA EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators. (±)19(20)-EpDPA Chemical Structure
  94. GC41202 (±)4-HDHA (±)4-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. (±)4-HDHA Chemical Structure
  95. GC41203 (±)7(8)-EpDPA Docosahexaenoic acid is the most abundant ω-3 fatty acid in neural tissues, especially in the brain and retina. (±)7(8)-EpDPA Chemical Structure
  96. GC41204 (±)7-HDHA

    (±)7-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.

     (±)7-HDHA Chemical Structure
  97. GC41205 (±)8-HDHA (±)8-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. (±)8-HDHA Chemical Structure
  98. GC33544 (±)-Methotrimeprazine (D6) (dl-Methotrimeprazine D6)

    (±)-Levomepromazina D6 ((±)-Metotrimeprazina D6) es la metotrimeprazina etiquetada con deuterio, que es un antagonista del receptor de dopamina D3 e histamina H1.

     (±)-Methotrimeprazine (D6) (dl-Methotrimeprazine D6) Chemical Structure
  99. GC31026 (±)-Tazifylline (±)-Taziphylline es un antagonista del receptor H1 de histamina potente, selectivo y de acción prolongada. (±)-Tazifylline Chemical Structure
  100. GN10155 (+)- Corydaline (+)- Corydaline Chemical Structure
  101. GC13156 (+)-AJ 76 hydrochloride

    Antagonista del receptor de dopamina

     (+)-AJ 76 hydrochloride Chemical Structure

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