Succinyladenosine (Synonyms: N6-Succinyl adenosine) |
| Catalog No.GC61614 |
Succinyladenosine, the metabolic product of dephosphorylation of intracellular adenylosuccinic acid (S-AMP) by cytosolic 5-nucleotidase, is a biochemical marker of adenylosuccinase (ASL) deficiency.
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Cas No.: 4542-23-8
Sample solution is provided at 25 µL, 10mM.
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Succinyladenosine, the metabolic product of dephosphorylation of intracellular adenylosuccinic acid (S-AMP) by cytosolic 5-nucleotidase, is a biochemical marker of adenylosuccinase (ASL) deficiency[1].
The presence of high concentrations of Succinyladenosine (S-Ado) in the human cerebrospinal fluid (CSF) in the range of 100-500 μmol/L is a diagnostic marker for inherited enzyme deficiency of ASL[1].
[1]. J Krijt, et al. Identification and Determination of Succinyladenosine in Human Cerebrospinal Fluid . J Chromatogr B Biomed Sci Appl. 1999 Apr 16;726(1-2):53-8.
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