Terrein (Synonyms: NSC 291308) |
| Catalog No.GC18458 |
Terrein is a fungal metabolite produced by A.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 582-46-7
Sample solution is provided at 25 µL, 10mM.
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Terrein is a fungal metabolite produced by A. terreus with diverse biological activities. It reduces melanin production in Mel-Ab mouse melanocytes in a dose-dependent manner via ERK activation and downregulation of microphthalmia-associated transcription factor (MITF). Terrein inhibits proliferation of human keratinocytes and thins the epidermis in a skin equivalent model of psoriasis vulgaris. It is antimicrobial, inhibiting the growth of S. aureus, A. hydrophila, E. faecalis, A. flavus, A. alternata, B. sorokiniana, and P. drechsleri (MICs = 1-40 μg/ml). Terrein also inhibits growth of A549 lung cancer cells in a dose-dependent manner.
Review for Terrein
Average Rating: 5 (Based on Reviews and 20 reference(s) in Google Scholar.)
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