UNC1079 |
| Catalog No.GC19367 |
UNC1079 is the piperidine analog of UNC1021, as a structurally similar but significantly less potent inhibitor for use as a negative control in cellular studies.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1418741-86-2
Sample solution is provided at 25 µL, 10mM.
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UNC1079 is the piperidine analog of UNC1021, as a structurally similar but significantly less potent inhibitor for use as a negative control in cellular studies. Target: L3MBTL3The low anticipated affinity of UNC1079 was confirmed, as it demonstrated an activity versus L3MBTL3 of > 10 uM by AlphaScreen, which is >1000-fold weaker than UNC1215. UNC1079 also displays weak binding by ITC.
References:
[1]. James LI, et al. Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain. Nat Chem Biol. 2013 Mar;9(3):184-91.
Average Rating: 5 (Based on Reviews and 9 reference(s) in Google Scholar.)
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