Home>>Lipids>> Prostaglandins>>11-deoxy-11-methylene-15-keto Prostaglandin D2

11-deoxy-11-methylene-15-keto Prostaglandin D2 (Synonyms: 11deoxy11methylene15keto PGD2)

Catalog No.GC41879

Prostaglandin D2 (PGD2) is one of the five primary enzymatic prostaglandins derived directly from PGH2.

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11-deoxy-11-methylene-15-keto Prostaglandin D2 Chemical Structure

Cas No.: 958759-75-6

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100μg
$82.00
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500μg
$371.00
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1mg
$658.00
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Sample solution is provided at 25 µL, 10mM.

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Quality Control & SDS

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Background

Prostaglandin D2 (PGD2) is one of the five primary enzymatic prostaglandins derived directly from PGH2. Many of the biological effects of PGD2 are transduced in vivo by a classical 7-transmembrane GPCR, the DP1 receptor. However, a second receptor, the chemokine-related CRTH2 receptor, also binds PGD2. This new receptor was recently identified on human eosinophils, where it binds selectively the PGD2 metabolite 13,14-dihydro-15-keto PGD2. 11-deoxy-11-methylene-15-keto PGD2 was prepared as a more chemically stable ligand for this receptor. There are no published studies of the pharmacological properties of 11-deoxy-11-methylene-15-keto PGD2.

Chemical Properties

Cas No. 958759-75-6 SDF
Synonyms 11deoxy11methylene15keto PGD2
Canonical SMILES O[C@@H](C1)[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/C(CCCCC)=O)C1=C
Formula C21H32O4 M.Wt 348.5
Solubility DMF: 100 mg/ml,DMSO: 100 mg/ml,Ethanol: 100 mg/ml,PBS (pH 7.2): 2 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 2.8694 mL 14.3472 mL 28.6944 mL
5 mM 0.5739 mL 2.8694 mL 5.7389 mL
10 mM 0.2869 mL 1.4347 mL 2.8694 mL
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Review for 11-deoxy-11-methylene-15-keto Prostaglandin D2

Average Rating: 5 ★★★★★ (Based on Reviews and 14 reference(s) in Google Scholar.)

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