6α-Prostaglandin I1 (Synonyms: 6αPGI1, 5,6αdihydro PGI2) |
| Catalog No.GC40585 |
6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 62777-90-6
Sample solution is provided at 25 µL, 10mM.
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6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions. 6α-PGI1 promotes cyclic AMP accumulation in human thyroid slices and cells in a concentration dependent manner. However, it is about 10-fold less potent than the β-isomer and 100-fold less potent than PGI2 in eliciting the response. 6α-PGI1 exhibits an IC50 of 350 ng/ml for inhibition of ADP-induced platelet aggregation, which is nearly 900-fold higher than that observed for PGI2 (0.4 ng/ml).
Average Rating: 5 (Based on Reviews and 3 reference(s) in Google Scholar.)
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