ARN 077 (URB913) (Synonyms: URB913) |
| Catalog No.GC31913 |
ARN 077 (URB913) is a potent and selective N-acylethanolamine acid amidase (NAAA) inhibitor with an IC50 of 7 nM for human NAAA.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1373625-34-3
Sample solution is provided at 25 µL, 10mM.
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ARN 077 is a potent and selective N-acylethanolamine acid amidase (NAAA) inhibitor with an IC50 of 7 nM for human NAAA[1]. ARN 077 significantly increases palmitoyl ethanolamine (PEA) levels within the CNS and has broad antinociceptive activity in mice and rats[2].
[1]. Sasso O, et al. Antinociceptive effects of the N-acylethanolamine acid amidase inhibitor ARN077 in rodent pain models. Pain. 2013 Mar;154(3):350-60. [2]. Davis MP, et al. Cannabinoids in pain management: CB1, CB2 and non-classic receptor ligands. Expert Opin Investig Drugs. 2014 Aug;23(8):1123-40.
Average Rating: 5 (Based on Reviews and 38 reference(s) in Google Scholar.)
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