CCR1 antagonist 9 |
| Catalog No.GC60678 |
CCR1 antagonist 9 is a potent and selective CCR1 antagonist with an IC50?of?6.8 nM in calcium flux assay.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1220026-26-5
Sample solution is provided at 25 µL, 10mM.
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CCR1 antagonist 9 is a potent and selective CCR1 antagonist with an IC50?of?6.8 nM in calcium flux assay[1].
CCR1 antagonist 9 (Compound 19e) blocks the CCR1 chemotaxis of THP-1 cells with an IC50 of 28 nM. CCR1 antagonist 9 also blocks hERG with an IC50 of 30 μM[1].
[1]. Harcken C, et al. Identification of novel azaindazole CCR1 antagonist clinical candidates. Bioorg Med Chem Lett. 2019 Feb 1;29(3):441-448.
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