Atezolizumab is an Fc-engineered , humanized, monoclonal antibody that targets programmed death ligand 1 (PD-L1). Atezolizumab prevents the binding of PD-L1 to receptors programmed death 1 (PD-1) and B7.

By searching deep in the field of cellular biology by using the microscopic aspects, we revealed the surprising molecule under the name of 3-Methyladenine (3-MA), a compound that does not have its recognization under the heading of DNA or proteins, but play a vital role in the front line of cellular processes.

In the ever-evolving landscape of biomedical research, a new star is rising, capturing the attention of scientists and researchers worldwide. This star is none other than Tat-NR2B9c, a peptide whose unique properties and potential applications are setting the stage for groundbreaking advancements in medicine and therapeutic treatment.

TAK-242 ethyl (6R)-6-[N-(2-chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate, also known as resatorvid, is a cyclohexene derivative and a small inhibitor molecule of TLR4 signaling, which was first represented as a novel anti-sepsis treatment that may inhibit the production of inflammatory mediators. Research on the mechanisms of action has revealed that TAK-242 specifically binds to Cys747 in the TIR domain of TLR4, which ensuingly prevents TLR4 from interacting with TIRAP.

Pseudomonas aeruginosa produces copious amounts of the redox-active tricyclic phenazine compound pyocyanin ( chloroform-soluble) that kills competing microbes and mammalian cells, especially during cystic fibrosis ,lung infection. Pyocyanin is responsible for the blue-green colour chacteristics of pseudomonas species. The pigment pyocyanin is composed of 2 subunits of N-methyl-1-hydroxyphenazine .

In the annals of medical research, serendipity often plays a pivotal role in leading scientists down unforeseen paths that dramatically alter our understanding of human health and disease. Such is the role of MPTP (1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine) hydrochloride, a compound whose story intertwined with the fates of a few, yet has illuminated the path for many in the battle against Parkinson’s disease. This blog article embarks on a journey through the discovery of MPTP hydrochloride, its profound impacts on neuroscience, and the ongoing quest to conquer neurodegenerative disorders.

In the vast expanse of natural remedies and health supplements, there lies a potent compound that has been quietly making waves in the wellness community: Forskolin. Extracted from the Coleus forskohlii plant, a botanical relative of mint, this remarkable compound has transcended its traditional uses to become a beacon of hope for those seeking natural ways to improve their health.

In the realm of molecular biology and genetic engineering, the delivery of genetic material into cells is a fundamental step that enables researchers to study gene function, protein expression, and even the potential treatment of genetic diseases.

In the intricate world of molecular biology, understanding the structure and function of proteins is paramount. Proteins, often adorned with various post-translational modifications, play crucial roles in virtually all biological processes.

A cell-permeable, potent, and selective blocker of necroptosis (EC50 = 494 nM in FADD-deficient Jurkat cells treated with TNF-α), a non apoptotic necrotic cell death pathway mediated by death-domain receptors (DRs) that offers neuroprotection in a murine model of ischemic brain injury.