Cinacalcet an FDA approved drug which kills bacteria by destroying bacterial membrane as well as respiratory metabolism and is used to treat secondary hyperparathyroidism and parathyroid cancer. It can also kill bacteria by producing reactive oxygen species (ROS). It was revealed by Limited Proteolysis -Small molecule mapping (LiP-SMap) that cinacalcet inhibits biofilm formation by targeting IcaR. Cinacalcet can partially remove the biofilm of drug-resistant S. aureus in an animal model it was revealed by in vitro and in vivo experiments . These findings suggest that cinacalcet has antibacterial and antibiofilm capabilities.

A ubiquitous metabolite that participates in numerous physiological processes, including transsulfuration, polyamine biosynthesis, and transmethylation is the ademetionine also known as S-adenosyl-L-methionine (AdoMet), SAM or SAMe ( Glpbio ).

A macrolide antibiotic, tylosin is active against gram-positive aerobic bacteria and mycoplasmas throughout a wide range of conditions. It is authorized for the treatment of a number of infectious disorders in cattle and poultry, including mastitis, respiratory conditions, and farm animal dysentery.

Introduction: RSM-932A, also known as TCD- 717, is a ChoKα asset, which targets the mortal choline kinase nascence, an enzyme involved in increased lipid metabolism of cancer cells. RSM-932A appears to have an altogether new medium of inhibition and is synergistic with respect to both choline and ATP. RSM-932A have in vitro inhibitory exertion in the low nanomolar range.

The sodium salt of palmitic acid, sodium palmitate ( Hexadecanoic acid sodium salt, Palmitic acid sodium salt) , produced during the process of fatty acid synthesis present in fats and waxes. It is produced synthetically and driven by palm oil. Plays major role as an emulsifier.

Brent R. Stockwell, the author of the origin of Ferroptosis, has written a review about research progress for the 10th anniversary of Ferroptosis, published in the journal Cell with a high impact factor of 66.85 (2022). The National Nature Foundation projects and the amount of money winning the bid in this direction are rising year by year, and the relevant research papers are also repeatedly topping the CNS! (Figure 1)

Alisol B (ALB), a triterpenoid compound extracted from Alisma, has been reported to ameliorate nonalcoholic steatohepatitis (NASH) and slow obesity.

Semaglutide is a polypeptide composed of 31 amino acids related by peptide bonds, with a molecular heaviness of 4114 g/mol. It actions as an agonist for glucagon-like peptide-1 receptors (GLP-1 R) and is functioned in the action of type 2 diabetes. Semaglutide purposes as a hypoglycemic agent, a GLP-1 receptor agonist, an anti-obesity mediator, a neuroprotective mediator, and want for food suppressant.

20-Hydroxyeicosatetraenoic acid (20-HETE) manufactured by forward thinkers Glpbio having Molecular Formula: C20H32O3 and Molecular Weight: 320.5 g/mol , is a remarkable arachidonic acid metabolite, playing a key role in many physiological and pathological activities.It is a quantitative and analytical standard that is guaranteed to meet the MaxSpec identity, purity, stability and concentration specifications.

SP2509 also known as HCI-2509 is a small low molecular weight organic compound that can enter into cells and interact with the biological targets .It is used as research tool to study various diseases and biological processes including cancer , inflammation and neurological disorders .