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(E)-2-Decenoic acid Catalog No.GC15373

Fatty acid identified in royal jelly

Size Price Stock Qty
10mM (in 1mL DMSO)
$38.00
In stock
25mg
$38.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Quality Control

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Chemical Properties

Cas No. 334-49-6 SDF
Synonyms trans-2-Decenoic acid
Chemical Name (E)-dec-2-enoic acid
Canonical SMILES CCCCCCCC=CC(=O)O
Formula C10H18O2 M.Wt 170.25
Solubility ≥8.8 mg/mL in DMSO, ≥161.4 mg/mL in EtOH, <3.01 mg/mL in H2O Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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Background

(E)-2-Decenoic acid is an interesting fatty acid isolated from royal jelly secretions of honey bees.

(E)-2-Decenoic acid is isolated along with 10-hydroxy-trans-2-decenoic acid, a fatty acid unique to royal jelly. (E)-2-Decenoic acid and 10-hydroxy-trans-2-decenoic acid are both described to demonstrate estrogenic activity, where the fatty acids demonstrate inhibition of 17β-estradiol binding to estrogen receptor-β.

References:
[1]. Naumowicz M, Petelska AD, Figaszewski ZA.Impedance analysis of complex formation equilibria in phosphatidylcholine bilayers containing decanoic acid or decylamine.Cell Biochem Biophys. 2011 Sep;61(1):145-55.
[2]. Kumar A, Singh S, Jain S, Kumar P.Synthesis, antimicrobial evaluation, QSAR and in Silico ADMET studies of decanoic acid derivatives.Acta Pol Pharm. 2011 Mar-Apr;68(2):191-204.
[3]. Petelska AD, Figaszewski ZA.Interfacial tension of the lipid membrane formed from phosphatidylcholine-decanoic acid and phosphatidylcholine-decylamine systems.J Membr Biol. 2011 May;241(2):103-8.
[4]. Hattori N et al.Royal jelly and its unique fatty acid, 10-hydroxy-trans-2-decenoic acid, promote neurogenesis by neural stem/progenitor cells in vitro. Biomed Res. 2007 Oct;28(5):261-6.
[5]. Suzuki KM et al. Estrogenic activities of Fatty acids and a sterol isolated from royal jelly. Evid Based Complement Alternat Med. 2008 Sep;5(3):295-302.