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EF24

Catalog No.GC64496

EF24 is a curcumin analogue with greater anti-tumor efficacy and oral bioavailability via deactivation of the MAPK/ERK signaling pathway in oral squamous cell carcinoma (OSCC). EF24 treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK.

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EF24 Chemical Structure

Cas No.: 342808-40-6

Size Price Stock Qty
10mM (in 1mL DMSO)
$85.00
In stock
5mg
$77.00
In stock
10mg
$137.00
In stock
25mg
$287.00
In stock
50mg
$455.00
In stock
100mg
$686.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

EF24 is a curcumin analogue with greater anti-tumor efficacy and oral bioavailability via deactivation of the MAPK/ERK signaling pathway in oral squamous cell carcinoma (OSCC). EF24 treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK[1][2].

[1]. Lelli D, et al. Curcumin and treatment of melanoma: The potential role of microRNAs. Biomed Pharmacother. 2017 Apr;88:832-834. [2]. Mosley CA, et al. Highly active anticancer curcumin analogues. Adv Exp Med Biol. 2007;595:77-103.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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