(1α,1'S,4β)-Lanabecestat (Synonyms: (1α,1'S,4β)-AZD3293; (1α,1'S,4β)-LY3314814) |
| Catalog No.GC38489 |
(1α,1'S,4β)-Lanabecestat ((1α,1'S,4β)-AZD3293) a less active enantiomer of Lanabecestat.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1384082-96-5
Sample solution is provided at 25 µL, 10mM.
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(1α,1'S,4β)-Lanabecestat ((1α,1'S,4β)-AZD3293) is a Beta site APP Cleaving Enzymel (BACE1) inhibitor extracted from patent WO2012087237A1, compound 20a, has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay), respectively[1].
[1]. Gabor Csjernyik, et al. Compounds and their use as bace inhibitors. WO2012087237A1.
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