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Glycoursodeoxycholic acid (Ursodeoxycholylglycine) (Synonyms: GUDCA, Ursodeoxycholyl Glycine)

Catalog No.GC33687

Glycoursodeoxycholic acid (Ursodeoxycholylglycine), a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid.

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Glycoursodeoxycholic acid (Ursodeoxycholylglycine) Chemical Structure

Cas No.: 64480-66-6

Size Price Stock Qty
10mM (in 1mL DMSO)
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid.In Vitro: The antioxidant compound glycoursodeoxycholic acid (GUDCA) fully abrogates UCB-induced cytochrome c oxidase inhibition and significantly prevents oxidative stress, metabolic alterations, and cell demise[1].GUDCA has shown therapeutic efficacy in neurodegenerative models and diseases. Increased cytosolic SOD1 inclusions were observed in 4 DIV NSC-34/hSOD1(G93A) cells together with decreased mitochondria viability, caspase-9 activation, and apoptosis[2]. Glycoursodeoxycholic acid shows preventive and restorative effects against unconjugated bilirubin -induced blood-brain barrier disruption and damage to human brain microvascular endothelial cells[3].


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Average Rating: 5 ★★★★★ (Based on Reviews and 9 reference(s) in Google Scholar.)

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