|GSK467 Catalog No.GC34604|
Sample solution is provided at 25 µL, 10mM.
GlpBio Products Cited In Reputable Papers
|Cas No.||1628332-52-4||SDF||Download SDF|
|Solubility||DMSO : 20.83 mg/mL (65.23 mM; Need ultrasonic);H2O : < 0.1 mg/mL (insoluble)||Storage||Store at -20°C|
|General tips||For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.|
|Shipping Condition||Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
GSK467 is a selective KDM5 (JARID1) inhibitor with a ki of 10 nM for KDM5B, shows 180-fold selectivity for KDM4C and no measurable inhibitory effects toward KDM6 or other Jumonji family members. ki: 10 nM (KDM5B)
. Johansson C, et al. Structural analysis of human KDM5B guides histone demethylase inhibitor development. Nat Chem Biol. 2016 Jul;12(7):539-45.