TN-16 (Synonyms: NSC 239274) |
| Catalog No.GC18763 |
TN-16 is an inhibitor of microtubule polymerization (IC50 = 0.4-1.7 uM).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 33016-12-5
Sample solution is provided at 25 µL, 10mM.
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TN-16 is an inhibitor of microtubule polymerization (IC50 = 0.4-1.7 uM). It blocks taxol-induced assembly of tubulin (IC50 = 6 uM) and blocks colchicine binding to tubulin. Like colchicine, TN-16 inhibits alkylation of tubulin. TN-16 induces metaphase arrest in renal cell carcinoma cells. TN-16 can be used in combination with other inhibitors to enhance the efficiency of human artificial chromosome transfer to recipient cells.
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Average Rating: 5 (Based on Reviews and 10 reference(s) in Google Scholar.)
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