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IHR 1

Catalog No.GC50201

Potent Smo antagonist

Products are for research use only. Not for human use. We do not sell to patients.

IHR 1 Chemical Structure

Cas No.: 548779-60-8

Size Price Stock Qty
10 mg
$215.00
In stock
50 mg
$900.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Potent Smo antagonist (IC50 = 7.6 nM). Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro. Fluorescent Analog also available.

Fan et al (2014) The Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation. Chem.Biol. 21 1680 PMID:25484239

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Average Rating: 5 ★★★★★ (Based on Reviews and 35 reference(s) in Google Scholar.)

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