IHR 1 |
Catalog No.GC50201 |
Potent Smo antagonist
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 548779-60-8
Sample solution is provided at 25 µL, 10mM.
Potent Smo antagonist (IC50 = 7.6 nM). Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro. Fluorescent Analog also available.
Fan et al (2014) The Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation. Chem.Biol. 21 1680 PMID:25484239
Average Rating: 5
(Based on Reviews and 35 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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