λ-Carrageenan |
| Catalog No.: GC19401 |
λ-Carrageenan is a naturally occurring compound
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
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Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
λ-Carrageenan is a naturally occurring compound which has been used to to generate and study models of inflammation and arthritic pain. Unlike κ- and ι-carageenans (sc-213226 and sc-216083, respectively), λ-carrageenans do not form helices and are non-gelling.
Reference
1. Sedgwick, A D., et al., 1986. A comparison of air pouch, sponge and pleurisy models of acute carrageenan inflammation in the rat. Agents and actions. 18(3-4): 439-46. PMID: 3463171
2. Morris, Christopher J., et al., 2003. Carrageenan-induced paw edema in the rat and mouse. Methods in molecular biology (Clifton, N.J.). 225(): 115-21. PMID: 12769480
3. Michel, Gurvan., et al., 2006. Bioconversion of red seaweed galactans: a focus on bacterial agarases and carrageenases. Applied microbiology and biotechnology. 71(1): 23-33. PMID: 16550377
4. Gabriel, A F., et al., 2007. The CatWalk method: a detailed analysis of behavioral changes after acute inflammatory pain in the rat. Journal of neuroscience methods. 163(1): 9-16. PMID: 17382401
5. Peter-Szabo, Mihaly., et al., . Quantitative characterization of a repeated acute joint inflammation model in rats. Clinical and experimental pharmacology & physiology. 34(5-6): 520-6. PMID: 17439426
| Cas No. | 9064-57-7 | SDF | |
| Synonyms | Gelatin | ||
| Chemical Name | [5-[4,5-dihydroxy-6-(hydroxymethyl)-3-sulfonatooxyoxan-2-yl]oxy-2,4-dihydroxy-6-(sulfonatooxymethyl)oxan-3-yl] sulfate | ||
| Canonical SMILES | C(C1C(C(C(C(O1)OC2C(OC(C(C2O)OS(=O)(=O)[O-])O)COS(=O)(=O)[O-])OS(=O)(=O)[O-])O)O)O | ||
| Formula | C12H19O20S3-3 | M.Wt | 579.46 |
| Solubility | Soluble in DMSO | Storage | Store at RT |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. | ||
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
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Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Average Rating: 5 (Based on Reviews and 31 reference(s) in Google Scholar.)
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