Mabuterol |
Catalog No.GC44112 |
Mabuterol is an agonist of the β2-adrenergic receptor (β2-AR).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 56341-08-3
Sample solution is provided at 25 µL, 10mM.
Mabuterol is an agonist of the β2-adrenergic receptor (β2-AR). It induces relaxation of isolated tracheal muscle in guinea pigs and inhibits bronchoconstriction in a guinea pig model of experimental asthma. Administration of mabuterol decreases blood pressure and increases heart rate in a dose-dependent manner in rats, cats, and dogs. These effects are reversed by the selective β2-AR antagonist ICI 118551 , indicating mabuterol is acting at β2-ARs. At concentrations ≥1 μM, mabuterol acts as a β1-AR antagonist in isolated dog right atria.
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