Myrothecine A |
| Catalog No.GC45958 |
A trichothecene mycotoxin
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 910292-40-9
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
Myrothecine A is a trichothecene mycotoxin that has been found in M. roridum and has anticancer activities.1,2 It inhibits proliferation of A549, MCF-7, HepG2, and SMMC-7721 cancer cells (IC50s = 95, 70, 60, and 25 μM, respectively).1 Myrothecine A (50 μM) induces G1 cell cycle arrest in HepG2 cells, as well as increases Bax and cleaved caspase-3, -5, and -8 levels and induces apoptosis in SMMC-7721 cells.1,2
|1. Lin, T., Wang, G., Zhou, Y., et al. Structure elucidation and biological activity of two new trichothecenes from an endophyte, Myrothecium roridum. J. Agric. Food Chem. 62(25), 5993-6000 (2014).|2. Song, H., Fu, Y., Wan, D., et al. Mytoxin B and myrothecine A induce apoptosis in human hepatocarcinoma cell line SMMC-7721 via PI3K/Akt signaling pathway. Molecules 24(12), E2291 (2019).
Average Rating: 5 (Based on Reviews and 5 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *