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Nemadipine A

Catalog No.GC44361

Nemadipine A is an L-type calcium channel blocker that induces morphological and growth defects in wild-type C.

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Nemadipine A Chemical Structure

Cas No.: 54280-71-6

Size Price Stock Qty
5mg
$94.00
In stock
10mg
$180.00
In stock
25mg
$425.00
In stock
50mg
$802.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Nemadipine A is an L-type calcium channel blocker that induces morphological and growth defects in wild-type C. elegans and those with hypoexpression of egl-19, which encodes the only L-type calcium channel α1-subunit in the C. elegans genome. It also inhibits L-type calcium channels in chick ciliary neurons. Nemadipine A increases TRAIL-induced cytotoxicity and synergistically enhances caspase-8 and caspase-3 activation in a concentration-dependent manner in H1299 lung adenocarcinoma cells. It also decreases Survivin expression when used alone or in combination with TRAIL in A549 cells.

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Average Rating: 5 ★★★★★ (Based on Reviews and 20 reference(s) in Google Scholar.)

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