Home>>Signaling Pathways>> Proteases>> Lipoxygenase>>S-(+)-Marmesin ((+)-Marmesin)
S-(+)-Marmesin ((+)-Marmesin) Catalog No.GC30027

Size Price Stock Qty
5 mg
$122.00
In stock
10 mg
$207.00
In stock
25 mg
$414.00
In stock
50 mg
$702.00
In stock
100 mg
$1,035.00
In stock

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Sample solution is provided at 25 µL, 10mM.

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Chemical Properties

Cas No. 13849-08-6 SDF Download SDF
Synonyms N/A
Chemical Name N/A
Canonical SMILES O=C1C=CC2=CC3=C(O[C@H](C(C)(O)C)C3)C=C2O1
Formula C14H14O4 M.Wt 246.26
Solubility DMSO : 2 mg/mL (8.12 mM; Need ultrasonic) Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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Background

S-(+)-Marmesin is a natural coumarin, exhibiting COX-2/5-LOX dual inhibitory activity.

S-(+)-Marmesin ((+)-marmesin) shows affinity at the recombinant psoralen synthase, with a Km of 1.5 ± 0.5 μM, exceeding the substrate affinities of other enzymes of the CYP71 subfamily involved in plant secondary metabolism[1]. S-(+)-Marmesin ((+)-marmesin) shows COX-2/5-LOX dual inhibitory activity[2].

[1]. Larbat R, et al. Molecular cloning and functional characterization of psoralen synthase, the first committed monooxygenase of furanocoumarin biosynthesis. J Biol Chem. 2007 Jan 5;282(1):542-54. Epub 2006 Oct 26. [2]. Kim JS, et al. Chemical constituents of the root of Dystaenia takeshimana and their anti-inflammatory activity. Arch Pharm Res. 2006 Aug;29(8):617-23.