SAHA-d5 (Synonyms: Suberoylanilide Hydroxamic Acid-d5, Vorinostat-d5) |
| Catalog No.GC44866 |
SAHA-d5 (SAHA-d5) is the deuterium labeled Vorinostat.
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Cas No.: 1132749-48-4
Sample solution is provided at 25 µL, 10mM.
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SAHA-d5 contains five deuterium atoms at the 2, 3, 4, 5, and 6 positions. It is intended for use as an internal standard for the quantification of SAHA by GC- or LC-MS. SAHA is a histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. It inhibits class I, II, and IV HDACs at 50-200 nM and arrests cell growth in a wide variety of transformed cells in culture at 2.5-5.0 µM.
Average Rating: 5 (Based on Reviews and 25 reference(s) in Google Scholar.)
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