Mitophagy
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Mitophagy is the selective degradation of mitochondria by autophagy.
Mitochondria are essential organelles that regulate cellular energy homeostasis and cell death. The removal of damaged mitochondria through autophagy, a process called mitophagy, is thus critical for maintaining proper cellular functions. Indeed, mitophagy has been recently proposed to play critical roles in terminal differentiation of red blood cells, paternal mitochondrial degradation, neurodegenerative diseases, and ischemia or drug-induced tissue injury.
Autophagy and mitophagy are important cellular processes that are responsible for breaking down cellular contents, preserving energy and safeguarding against accumulation of damaged and aggregated biomolecules.
Products Related to Mitophagy(84)
- GC74187Salicylic acid-13C6CAS: 1189678-81-6Purity: >97.00%
Salicylic acid-13C6 es el ácido salicílico marcado con 13c.
- GC80919AURKA-IN-4CAS: 89575-11-1Purity: >99.50%
AURKA-IN-4 is a Capsaicin -derived molecular glue targeting AURKA-PHB2, and acts as an inhibitor of Aurora kinase A ( AURKA ) and PHB2.
- GN10156Ginsenoside Rb1CAS: 41753-43-9Purity: >98.00%
Ginsenoside Rb1 is a natural active ingredient extracted from ginseng that can modulate the activity of multiple signaling pathways.
- GN10357ParthenolideCAS: 20554-84-1Purity: >98.00%
Parthenolide es un inhibidor de NF-κB con valores de IC 50 vpara las células Eca109, KYSE-510, SiHa y MCF-7 de approximadamente 10.3, 13.3, 8.42 y 9.54μM a 48h respectivamente.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC71260 | Dox-btn2 | 3026061-31-1 | >97.00% | |
Dox-btn2 es un derivado biotinilado de la doxorrubicina, con una etiqueta de biotina en el punto de conjuga la doxorrubicina en 3'-NH2. | ||||
| GC71423 | ATTECs Degrader 1 | - | >95.00% | |
ATTECs Degrader 1 (compuesto MT1) es un compuesto ATTECs. | ||||
| GC71451 | MTX115325 | 2750895-97-5 | >99.00% | |
MTX115325 (ejemplo 1) es un inhibide la USP30 (IC50=12 nM) con actividad neuroprotectora. | ||||
| GC71492 | WJ-39 | 3009908-95-3 | >99.00% | |
WJ-39 es un inhibide la aldose reductasa (AR). | ||||
| GC74187 | Salicylic acid-13C6 | 1189678-81-6 | >97.00% | |
Salicylic acid-13C6 es el ácido salicílico marcado con 13c. | ||||
| GC80919 | AURKA-IN-4 | 89575-11-1 | >99.50% | |
AURKA-IN-4 is a Capsaicin -derived molecular glue targeting AURKA-PHB2, and acts as an inhibitor of Aurora kinase A ( AURKA ) and PHB2. | ||||
| GC81846 | Nivitol | 869743-37-3 | >98.00% | |
Nivitol (UP302) is a natural phenolic compound discovered from Dianella ensifolia and also acts as a Tyrosinase inhibitor. | ||||
| GN10156 | Ginsenoside Rb1 | 41753-43-9 | >98.00% | |
Ginsenoside Rb1 is a natural active ingredient extracted from ginseng that can modulate the activity of multiple signaling pathways. | ||||
| GN10257 | Naringin | 10236-47-2 | >99.50% | |
| GN10266 | Quercetin | 117-39-5 | >97.00% | |
La quercetina es un flavonoide dietético importante, presente en verduras, frutas, semillas, nueces, té y vino tinto. | ||||
| GN10331 | Polydatin | 27208-80-6 | >98.00% | |
Polydatin es un glucósido de estilo natural extraído de la medicina tradicional china Polygonum cuspidatum, y Polydatin es la forma glucósida del resveratrol | ||||
| GN10357 | Parthenolide | 20554-84-1 | >98.00% | |
Parthenolide es un inhibidor de NF-κB con valores de IC 50 vpara las células Eca109, KYSE-510, SiHa y MCF-7 de approximadamente 10.3, 13.3, 8.42 y 9.54μM a 48h respectivamente. | ||||