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Talaporfin sodium (ME2906) (Synonyms: Mono-L-aspartyl Chlorin e6, NPe6, Taporfin)

Catalog No.GC30097

Talaporfin (ME2906) sodium is a chlorin based photosensitizer. Talaporfin sodium (ME2906) can be used for the research of various cancers by using photodynamic therapy (PDT).

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Talaporfin sodium (ME2906) Chemical Structure

Cas No.: 220201-34-3

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Talaporfin (ME2906; NPe6) is a photosensitizer used in photodynamic therapy (PDT).Target: OthersTalaporfin is a photosensitizer used in photodynamic therapy (PDT). Talaporfin absorbs red light at 664 nm normally provided by a laser tuned to this wavelength [1]. Talaporfin was approved in Japan (in 2004) for PDT of lung cancer and marketed as Laserphyrin [2].

[1]. http://journals.lww.com/jto/Fulltext/2006/06000/Photodynamic_Therapy__PDT__for_Lung_Cancers.18.aspx [2]. http://meeting.ascopubs.org/cgi/content/abstract/24/18_suppl/7229

Chemical Properties

Cas No. 220201-34-3 SDF
Synonyms Mono-L-aspartyl Chlorin e6, NPe6, Taporfin
Canonical SMILES O=C([O-])C[C@@H](C([O-])=O)NC(C/C1=C2[C@@H](CCC([O-])=O)[C@H](C)C(/C=C3C(C)=C(C=C)/C(N/3)=C/C(C(C)=C/4CC)=NC4=C/C5=C(C)C(C([O-])=O)=C1N5)=N\2)=O.[Na+].[Na+].[Na+].[Na+]
Formula C38H37N5Na4O9 M.Wt 799.69
Solubility Water: 50 mg/mL (62.52 mM); DMSO: 2 mg/mL (2.50 mM) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).


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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Average Rating: 5 ★★★★★ (Based on Reviews and 7 reference(s) in Google Scholar.)

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