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Trehalose 6-phosphate (potassium salt)

Catalog No.GC45076

Trehalose 6-phosphate (potassium salt) Chemical Structure

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1mg
$38.00
In stock
5mg
$171.00
In stock
10mg
$295.00
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25mg
$567.00
In stock

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Sample solution is provided at 25 µL, 10mM.

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Background

Trehalose is a natural non-reducing disaccharide found in plants, invertebrates, fungi, and bacteria.[1] [2]  In addition to roles as an energy source and stress protectant, trehalose can function as a signaling molecule. [3][4] Trehalose 6-phosphate is an intermediate in the biosynthesis of trehalose. It is generated from UDP-glucose and glucose 6-phosphate by trehalose 6-phosphate synthase (TPS or otsA).[5] In plants, changes in trehalose 6-phosphate levels positively correlate with diurnal changes in sucrose and may regulate diverse processes, including starch degradation and flowering.[3][6]

Reference:
[1]. Walmagh, M., Zhao, R., and Desmet, T. Trehalose analogues: Latest insights in properties and biocatalytic production. International Journal of Molecular Sciences 16(6), 13729-13745 (2015).
[2]. Goddijn, O.J., Verwoerd, T.C., Voogd, E., et al. Inhibition of trehalase activity enhances trehalose accumulation in transgenic plants. Plant Physiology 113(1), 181-190 (1997).
[3]. Lunn, J.E., Delorge, I., Figueroa, C.M., et al. Trehalose metabolism in plants. Plant Journal 79(4), 544-567 (2014).
[4]. Henry, C., Bledsoe, S.W., Siekman, A., et al. The trehalose pathway in maize: Conservation and gene regulation in response to the diurnal cycle and extended darkness. Journal of Experimental Botany 65(20), 5959-5973 (2014).
[5]. Padilla, L., Krämer, R., Stephanopoulos, G., et al. Overproduction of trehalose: Heterologous expression of Escherichia coli trehalose-6-phosphate synthase and trehalose-6-phosphate phosphatase in Corynebacterium glutamicum. Applied and Environmental Microbiology 70(1), 370-376 (2004).
[6]. Wahl, V., Ponnu, J., Schlereth, A., et al. Regulation of flowering by trehalose-6-phosphate signaling in Arabidopsis thaliana. Science 339(6120), 704-707 (2013).

Chemical Properties

Cas No. 136632-28-5 SDF
Synonyms N/A
Chemical Name α-D-glucopyranosyl α-D-glucopyranoside 6-(dihydrogen phosphate), dipotassium salt, hydrate
Canonical SMILES OC[C@@H](O1)[C@@H](O)[C@H](O)[C@@H](O)[C@@]1([H])O[C@@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](COP([O-])([O-])=O)O2.[K+].[K+]
Formula C12H21O14P•2K M.Wt 498.5
Solubility 50mg/mL in water Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

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