WSP-5 (Synonyms: Washington State Probe-5) |
Catalog No.GC45162 |
WSP-5 is a fluorescent probe designed for the rapid detection of hydrogen sulfide (H2S) in biological samples and cells. λ ex/em =502/525 nm.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1593024-78-2
Sample solution is provided at 25 µL, 10mM.
WSP-5 (Washington State Probe-5) is a fluorescent probe containing active disulfide groups, specifically designed for rapid detection of hydrogen sulfide (H2S) in biological samples and within cells. H2S, like nitric oxide, has significant effects on mammalian immune, nervous, cardiovascular, and pulmonary systems. Through a reaction-based fluorescence turn-on strategy, WSP-5 selectively and rapidly reacts with H2S, generating fluorescence with excitation and emission maxima at 502 and 525 nm, respectively[1]. Compared with the three H2S probes WSP-1, CAY and P3, WSP-5 has the widest linear range of sensitivity, minimal interference to thiols and other analytes, the most stable in different pH environments, and can be used in Imaging H2S in live cell systems [2].
References:
[1] Peng, B., Chen, W., Liu, C., et al. Fluorescent probes based on nucleophilic substitution-cyclization for hydrogen sulfide detection and bioimaging[J]. Chemistry 20(4), 1010-1016 (2014).
[2] Yingzhu Zhou, Dr. Federico Mazur,et al. Sensitivity and Selectivity Analysis of Fluorescent Probes for Hydrogen Sulfide Detection[J]. Chemistry – An Asian Journal
March 1, 2022.
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