Z-VAD-AMC (acetate) (Synonyms: Z-Val-Ala-Asp-AMC, Z-Val-Ala-Asp-7-amino-4-methylcoumarin) |
Catalog No.GC40151 |
Z-VAD-AMC is a fluorogenic substrate for caspase-1.
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Sample solution is provided at 25 µL, 10mM.
Z-VAD-AMC is a fluorogenic substrate for caspase-1. Upon enzymatic cleavage by caspase-1, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify caspase-1 activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
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