PAD
Products for PAD
- Cat.No. Product Name Information
- GC35480 BB-Cl-Amidine hydrochloride BB-Cl-Amidine hydrochloride is a peptidylarginine deminase (PAD) inhibitor.
- GC42910 BB-F-Yne BB-F-Yne is a cell-permeable derivative of the protein arginine diminase (PAD) inhibitor BB-Cl-amidine that contains an alkyne moiety for use in click chemistry reactions.
- GC48495 BMS-P5 BMS-P5 is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor. BMS-P5 blocks MM-induced NET formation and delays progression of MM in a syngeneic mouse model.
- GC43202 CAY10723 CAY10723 is a potent protein arginine deiminase 2 (PAD2) inhibitor and has excellent PAD2-selectivity.
- GC47050 CAY10727 A PAD3 inhibitor
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GC35706
Cl-amidine
Cl-amidine (N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-l-ornithine amide), is a PAD4 inactivator with enhanced potency.
- GC18925 Cl-Amidine (hydrochloride) Cl-amidine is an inhibitor of protein arginine deiminases (PAD; IC50s = 0.8, 6.2, and 5.9 uM for PAD1, PAD3, and PAD4 in vitro, respectively).
- GC11032 Cl-Amidine (trifluoroacetate salt) Cl-Amidine (trifluoroacetate salt) is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3, and PAD4, respectively.
- GC43651 F-Amidine (trifluoroacetate salt) F-amidine is an inhibitor of protein arginine deiminases (PADs) that is selective for PAD1 and PAD4 (IC50s = 29.5, 350, and 21.6 μM for PAD1, PAD3, and PAD4 in vitro, respectively).
- GC43788 GSK121 (trifluoroacetate salt) GSK-121 Trifluoroacetates a selective PAD4 inhibitor.
- GC43789 GSK199 (hydrochloride) GSK199 (hydrochloride) is a reversible and selective PAD4 inhibitor with an IC50 of 200 nM in the absence of calcium.
-
GC19184
GSK484 hydrochloride
GSK484 is a selective PAD4 inhibitor with an IC50 of 50 nM without calcium.
- GC45548 Photoswitchable PAD Inhibitor (technical grade)
- GC32303 Streptonigrin (Bruneomycin) Streptonigrin (Bruneomycin) (Bruneomycin), a natural product produced by Streptomyces flocculus, possesses both anti-tumor and anti-bacterial activity.
- GC33261 YW3-56
- GC48263 YW3-56 (hydrochloride) (technical grade) A PAD2 and PAD4 inhibitor