Home>>Tazarotenic Acid
Tazarotenic Acid Catalog No.GC45001

Size Price Stock Qty
5mg
$107.00
In stock
10mg
$204.00
In stock
25mg
$483.00
In stock
50mg
$857.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Chemical Properties

Cas No. 118292-41-4 SDF Download SDF
Synonyms N/A
Chemical Name N/A
Canonical SMILES OC(C1=CC=C(C#CC2=CC(C(C)(C)CCS3)=C3C=C2)N=C1)=O
Formula C19H17NO2S M.Wt 323.4
Solubility Soluble in DMSO Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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Background

Tazarotenic acid is an active metabolite of tazarotene, an acetylenic retinoid prodrug that induces epidermal hyperplasia with an ED50 value of 100 nM. Tazarotenic acid selectively binds retinoic acid receptors (RAR-β and RAR-γ) in vitro. It has a relatively short elimination half-life of one to two hours and is metabolized by cytochrome P450 (CYP) isoforms CYP2C8, CYP26A1, and CYP26B1.