BTS (Synonyms: N-Benzyl-p-toluenesulfonamide, NSC 37123) |
| Catalog No.GC16189 |
potent inhibitor of Ca2+-stimulated myosin S1 ATPase
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1576-37-0
Sample solution is provided at 25 µL, 10mM.
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BTS is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 ~ 5 μM) and reversibly blocks the gliding motility. IC50 value: 5 uMTarget: Ca2+-stimulated myosin S1 ATPaseBTS also weakens myosin’s interaction with F-actin. BTS is much less effective in suppressing contraction in rat myocardial or rabbit slow twitch muscle and has no effect on platelet myosin II.
References:
[1]. Cheung A, et al. A small-molecule inhibitor of skeletal muscle myosin II. Nat Cell Biol. 2002 Jan;4(1):83-8.
Average Rating: 5 (Based on Reviews and 17 reference(s) in Google Scholar.)
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